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The Buffalo Bills could face a significant challenge heading into their Week 5 matchup against the Los Angeles Rams. Wide receiver DJ Moore missed another practice Thursday as the team monitored his shoulder injury.
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The update raises questions about Moore’s availability for Sunday’s game. With quarterback Josh Allen leading a 3-1 Buffalo team, losing a key receiving option could force the offense to adjust against a Rams defense preparing for the matchup.
The Bills have limited time to assess Moore’s condition before traveling to Los Angeles.
Thursday injury report pic.twitter.com/eKp7Jz02Zy
— Buffalo Bills PR (@BuffaloBillsPR) October 8, 2026
The Bills confirmed that Moore did not participate in Thursday’s practice because of a shoulder issue. It was his second consecutive missed practice, according to the supplied injury notes.
That absence is worth watching, particularly because shoulder injuries can affect a receiver’s ability to accelerate, separate from defenders and run routes at full speed. However, missing practice does not automatically rule Moore out for Sunday’s game.
Moore’s potential absence would leave Allen without an important option in the passing game. Buffalo could look to receivers such as Khalil Shakir and Keon Coleman for additional opportunities if Moore cannot play.
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The matchup also presents a challenge because the Rams are coming off a 24-20 road victory over the Philadelphia Eagles, according to the supplied notes. Los Angeles is looking to build on that result, while Buffalo hopes to maintain its strong start.
The Bills’ offensive approach could change depending on Moore’s availability. Allen may need to spread targets among his other receivers, while running back James Cook could play an important role in keeping the offense balanced.
Still, the biggest question is whether Moore can return to practice before Sunday’s game. His consecutive absences make his status a key storyline, but the team has not confirmed that he will miss the matchup.
Buffalo will have to evaluate his progress before making a final decision. Until then, the Bills’ plans against Los Angeles remain tied in part to the health of one of their receiving options.
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This story was originally published October 9, 2026 at 7:40 AM.