{"id":2041,"date":"2026-05-15T05:31:19","date_gmt":"2026-05-15T05:31:19","guid":{"rendered":"https:\/\/sandiegorelocationnews.com\/index.php\/2026\/05\/15\/the-49ers-schedule-is-out-here-are-our-predictions-for-game-of-the-year-and-more\/"},"modified":"2026-05-15T05:31:19","modified_gmt":"2026-05-15T05:31:19","slug":"the-49ers-schedule-is-out-here-are-our-predictions-for-game-of-the-year-and-more","status":"publish","type":"post","link":"https:\/\/sandiegorelocationnews.com\/index.php\/2026\/05\/15\/the-49ers-schedule-is-out-here-are-our-predictions-for-game-of-the-year-and-more\/","title":{"rendered":"The 49ers schedule is out. Here are our predictions for game of the year and more"},"content":{"rendered":"
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The 49ers have released their full schedule for the 2026 regular season. So, naturally, it\u2019s time to get out the crystal ball.<\/p>\n

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Complete with 38,000-plus miles of air travel including international stops in Australia and Mexico, the slate of games includes two divisional games apiece against the reigning Super Bowl champion Seattle Seahawks and NFC runners-up in the Los Angeles Rams, plus other intriguing matchups pitting San Francisco against NFC East and AFC West.<\/p>\n

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Now it\u2019s prediction time. Here\u2019s what The Sacramento Bee expects will be the…<\/p>\n

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Must-watch Game of the Year<\/h2>\n

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It\u2019s easy to point to any matchups with the Seahawks and Rams, given Seattle won the Super Bowl (at Levi\u2019s Stadium, no less) and the Rams went to the NFC title game.<\/p>\n

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But the must-watch game on the schedule is Week 17 against the Eagles. There is real hatred between these two teams and fanbases, plus \u201cBig Dom\u201d is coming to Levi\u2019s Stadium with Dre Greenlaw back in red and gold.<\/p>\n

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There\u2019s always drama around the Eagles, and surely 49ers fans would love to put the nail in the Nick Sirianni and\/or Jalen Hurts eras.<\/p>\n

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Sleeper-pick Game of the Year<\/h2>\n

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Don\u2019t sleep on Week 4 against the Broncos.<\/p>\n

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There are a lot of high-profile games on the schedule, including against the Chiefs, Cowboys and former geographic rival Raiders. But don\u2019t forget Denver hosted the AFC title game last year and may have put been a stronger opponent for Seattle in the Super Bowl than the New England Patriots had Nix not gotten hurt. The Broncos are talented and well-coached.<\/p>\n

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The 49ers travel to play the Seahawks the following week, so this could be a trap game early in the season.<\/p>\n

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