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Week 6 of the 2026 college football season features 55 games from Thursday, Oct. 8, through Saturday, Oct. 10. Athlon Sports is back with predictions and picks for every contest.
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The sixth full weekend of the ’26 season started with Troy beating Southern Miss on Tuesday night, along with Jacksonville State (Kennesaw State) and FIU (New Mexico State) picking up wins in CUSA play. The action continues with four games on Thursday night, including South Florida-UTSA and South Alabama-Arkansas State. Five games are on tap for Friday. Florida State-Louisville and Iowa-Washington are the headliners, but Washington State-Utah State, Wyoming-San Jose State and Iowa State-BYU are intriguing.
A full slate of action on Saturday kicks off with Indiana-Nebraska, Texas A&M-Missouri, North Carolina-Pitt, Arizona-West Virginia, Wake Forest-NC State and South Carolina-Florida in the first window. The afternoon slate features the annual Red River Rivalry between Oklahoma-Texas. Additionally, Stanford-Notre Dame, Ole Miss-Vanderbilt, UCLA-Oregon and Houston-Kansas State headline the afternoon window.
The first night window includes LSU-Kentucky, North Dakota State-UNLV, Georgia-Alabama, USC-Penn State and Minnesota-Purdue. The late-night window is headlined by Hawaii-Arizona State, Kansas-Utah and Boise State-Fresno State.
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Athlon Sports’ Steven Lassan, Tyler Schuster and Kyle Wood make predictions for all 55 games in Week 6.
College Football Picks: Expert Predictions for Every Game in Week 6
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This story was originally published October 8, 2026 at 11:30 AM.