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The Week 2 NFL running back prop market has some young options worth targeting. Jeremiyah Love looks to build on a solid NFL debut, and Kaelon Black could benefit from a favorable game script in San Francisco, while Bhayshul Tuten gets another chance to lead Jacksonville’s backfield after an impressive opener.
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If you’re looking for the best NFL running back props to bet in Week 2, these three picks offer some interesting angles and manageable numbers to attack.
All odds are from DraftKings Sportsbook and are subject to change. DraftKings does not sponsor this content.
Best NFL RB Prop Bets for Week 2
Arizona Cardinals RB Jeremiyah Love 40+ Rushing Yards (+102)
Love didn’t need much work to make some noise in his NFL debut, turning 11 carries into 41 yards despite playing only 42.7% of Arizona’s offensive snaps. Seattle’s run defense is no picnic, but the rookie’s role should continue to grow after a solid opener. Love doesn’t need to suddenly become a workhorse, either. Give him another 10-to-12 carries and a little room to run, and he should have a chance to deliver.
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San Francisco 49ers RB Kaelon Black 10+ Rush Attempts (-107)
Black was a lot busier than expected in his NFL debut, leading San Francisco with 14 carries while playing 43.1% of the offensive snaps. He made those opportunities count, too, averaging 4.6 yards per carry. Now the 49ers enter Week 2 as 13.5-point favorites over Miami, which could mean an early seat for Christian McCaffrey if things get lopsided. That would leave Black with plenty of chances to handle the cleanup work.
Jacksonville Jaguars RB Bhayshul Tuten 50+ Rushing Yards (-113)
Tuten turned 15 carries into 66 yards against a tough Cleveland run defense. The second-year back showed some burst, and the Jaguars’ offensive line looked better than expected. Denver, meanwhile, was pushed around by Kenneth Walker III and Kansas City on Monday night. Tuten doesn’t need to turn into Walker overnight. Another steady workload should give him plenty of chances to take advantage of those cracks up front.
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This story was originally published September 18, 2026 at 5:00 AM.