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The Buffalo Bills are on the road Sunday afternoon as they travel to take on the Houston Texans in an AFC showdown during Week 1 of the 2026 NFL season.
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Buffalo enters Sunday’s game looking to grab a key victory on the road as the Bills begin a new chapter under head coach Joe Brady after firing Sean McDermott following their divisional round defeat last season.
Houston enters Sunday’s contest looking to grab a key home victory as they look to start the season strong and contend for the AFC South title.
While both teams are looking to grab a victory in Sunday afternoon’s matchup, each may be without multiple key players due to injuries.
Bills Injury Report: Will Keon Coleman Play?
The Bills have three players listed on their injury report, though wide receiver Keon Coleman is not one of them.
Of course, Coleman suffered a sprained right foot during Buffalo’s preseason opener that landed him in a walking boot, though he now is off the injury report completely and will play against the Texans.
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Friday injury report pic.twitter.com/XiZGw5u0Af
— Buffalo Bills PR (@BuffaloBillsPR) September 11, 2026
Buffalo has listed running back Ty Johnson as questionable due to a hamstring injury, and if he is sidelined, Ray Davis could have a larger role behind James Cook.
The Bills have also listed defensive back Jordan Hancock as questionable due to a quad injury while defensive lineman T.J. Sanders is questionable with a knee injury.
Texans Injury Report: Will Will Anderson Jr., Trent Brown Play?
The Texans have nobody listed on their injury report for Sunday’s matchup.
Of course, defensive end Will Anderson Jr. missed a practice earlier in the week due to rest while offensive lineman Trent Brown has been dealing with a wrist injury. However, both players are off the injury report and will play against the Bills.
Houston #Texans Friday Injury Report & Game Status Report for Week 1 vs. the Buffalo Bills: pic.twitter.com/1ZHae9LNbm
— Houston Texans PR (@TexansPR) September 11, 2026
Fans can catch Sunday afternoon’s matchup between the Bills and Texans from Reliant Stadium at 1 p.m. ET on CBS in most of the country. Check your local listings for games available in your area.
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This story was originally published September 13, 2026 at 5:00 AM.