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The Arizona Cardinals are at home Sunday afternoon as they host the Detroit Lions in a Week 5 NFC matchup.
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Arizona enters Sunday’s game with a 1-3 record after losing on the road to the New York Giants in Week 4.
In their loss to the Giants, Jacoby Brissett led the way for the Cardinals as he recorded 166 passing yards, two passing touchdowns and three interceptions while Michael Wilson added 95 receiving yards.
The Cardinals will try to bounce back Sunday as they face off against the Lions in a tough home matchup.
Detroit enters Sunday’s contest with a 2-2 record after losing on the road to the Carolina Panthers in Week 4.
Jared Goff led the way for the Lions in their loss to the Panthers as he ended the game with 412 passing yards and one passing touchdown while Jameson Williams recorded 102 receiving yards.
While both teams are looking to pick up a victory in Sunday afternoon’s matchup, each may be without multiple key players due to injuries.
Lions Injury Report
The Lions have five players listed on their injury report for Sunday’s game against the Cardinals.
Detroit has ruled out safety Brian Branch due to an Achilles injury while cornerback Rock Ya-Sin is out with a hamstring injury.
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#DETvsAZ injury report pic.twitter.com/T5iE5hwoIH
— Detroit Lions (@Lions) October 9, 2026
The Lions have also ruled out guard Ben Bartch (foot) and center Cade Mays (wrist) while defensive tackle Tyleik Williams is questionable with a foot injury.
Cardinals Injury Report: Will Jeremiyah Love Play?
The Cardinals have five players listed on their injury report, including wide receiver Marvin Harrison Jr.
Arizona has ruled out Harrison Jr. after informing him Saturday morning that he will be inactive as the team finalizes a deal to trade him, according to ESPN’s Adam Schefter.
Breaking: the Arizona Cardinals are finalizing a deal to trade WR Marvin Harrison, sources tell me and @RapSheet.
The team informed Harrison this morning that he will be inactive for Sunday’s game vs Detroit as details of the trade are finalized. pic.twitter.com/x6n0Hsfzzj
— Adam Schefter (@AdamSchefter) October 10, 2026
The Cardinals have also ruled out offensive lineman Isaiah Adams due to an ankle injury while safety Andrew Wingard is out with a knee injury.
Defensive lineman Walter Nolan III has been listed as questionable due to a calf injury while linebacker Karson Sharar is questionable with a hamstring injury.
The good news for the Cardinals is that running back Jeremiyah Love is off the injury report and will play despite being limited in practice earlier in the week with an ankle injury.
Fans can catch Sunday afternoon’s matchup between the Lions and Cardinals from State Farm Stadium at 4:25 p.m. ET on FOX in both teams’ home markets and select other locations across the country. Check local listings for games available in your area.
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This story was originally published October 11, 2026 at 9:30 AM.